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Male mice were exposed to ethylene oxide(Et0) at concentrations of 54, 360 mg/m3 for two hours a day, on six days a week for 14 weeks. The results of sperm abnormalities test in mice showed the mutation frequencies of both low (54 mg/m3) and high (360 mg/m3) concentration groups are abvious (They are 29.40±16.24, P