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糖尿病胃轻瘫(DGP)是糖尿病常见的慢性继发性并发症。其发病机制极其复杂,缺乏特效的治疗方法与药物。以往临床上常用甲氧氯普胺、多潘立酮和莫沙必利等促胃肠道动力药治疗DGP,虽取得了一定的效果,但疗程较长,停药后易复发。甲钴胺是内源性的辅酶B_(12),外源性给药可顺利渗入神经细胞内,促进核酸、蛋白、脂质的合成。本文分析了莫沙必利联合甲钴胺治疗DGP的疗效,现报告如下。
Diabetic gastroparesis (DGP) is a common chronic secondary complication of diabetes. The pathogenesis is extremely complex, the lack of special effects of treatment and drugs. In the past, metoclopramide, domperidone and mosapride commonly used in clinical treatment of gastrointestinal motility drug treatment of DGP, although achieved some results, but a longer course of treatment, easy to relapse after stopping. Mecobalamin is endogenous coenzyme B_ (12), exogenous administration can smoothly penetrate into nerve cells, and promote nucleic acid, protein, lipid synthesis. This article analyzes the mosapride combined with mecobalamin for the treatment of DGP, are as follows.