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头孢美唑为第二代头孢霉素类半合成抗生素,对β内酰胺酶高度稳定,杀菌作用迅速,具有抗菌谱广,稳定性好,血药浓度高等特点。近年来国内有文献报道其不良反应,现概述如下:1紫癜型药疹刘燕等报道,患男,83岁,因肺炎给予注射用头孢美唑2g+0.9%NS250ml静滴,bid。2天后四肢皮肤出现散在针尖大小暗红色瘀点,按之不褪色,以双下肢明显,即停药。改用美罗培南,并予对症
Cefmetazole is the second generation of cephalosporins semi-synthetic antibiotics, β-lactamase high stability, rapid bactericidal effect, with broad antibacterial spectrum, good stability, high plasma concentration. In recent years, domestic literature reports its adverse reactions, are summarized as follows: 1 purpura-type drug eruption Liu Yan and other reports, suffering from male, 83 years old, given for injection of cefmetazole 2g + 0.9% NS250ml intravenous infusion of pneumonia, bid. 2 days after the emergence of limbs scattered nose size scattered dark red petechia, according to no fade to obvious lower limbs, that is, withdrawal. Use Meropenem, and symptomatic