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氟化物係一种强烈的酵素毒,据各家报告,氟能抑制烯酵化酶(Lipmann,Loh-mann),胆鹼酯酶(Matthes),骨磷酸化酶(Kay,Rosenheim)和脱氢辅酶Ⅰ、Ⅱ系统(DPN,TPN)(Adler et al)等。因此,在氟化物中毒时,可以产生各种物质代谢和机能的障礙,其中包括肌乳酸合量的减少或消失,血钙下降,血磷上升,CO_2的产量不足,组织内之醋醯胆鹼的含量升高,肝功能减退以及骨骼与牙齿的脱钙变化。关于氟
Fluoride is a strong enzyme toxin, according to reports, fluorine can inhibit the enzyme (Lipmann, Loh-mann), cholinesterase (Matthes), osteophosphorylase (Kay, Rosenheim) and dehydrogenation Coenzyme Ⅰ, Ⅱ system (DPN, TPN) (Adler et al) and so on. Therefore, fluoride poisoning, can produce a variety of material metabolism and dysfunction, including the amount of muscle lactate decreased or disappeared, decreased blood calcium, phosphorus increased, insufficient production of CO_2, the organization of vinegar choline Increased levels of liver dysfunction and decalcification of bone and teeth changes. About fluorine