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目的探讨薄层液基细胞学和阴道镜筛查宫颈病变的临床价值。方法选择2010-2012年在丹阳市第二人民医院妇科就诊的5937例患者,宫颈病变筛查分别采用薄层液基细胞学(TCT)检测和阴道镜检查,对TCT检测为不明意义的不典型鳞状上皮(ASCUS)、鳞状上皮内病变(SIL)、鳞状细胞癌(SCC),阴道镜检测为异常图像的病例行宫颈活组织病理学检查。结果 268例TCT为ASCUS以上者,其中病理诊断慢性宫颈炎219例(符合率88.1%),宫颈上皮内瘤变Ⅰ级34例(符合率67.6%),宫颈上皮内瘤变Ⅱ-Ⅲ级13例(符合率76.9%),宫颈癌2例(符合率100%)。1111例阴道镜异常图像,其中病理诊断慢性宫颈炎993例(符合率96.8%),宫颈上皮内瘤变115例(符合率90.4%),宫颈癌3例(符合率66.7%)。结论 TCT检测与宫颈活组织病理诊断结果总符合率83.2%,阴道镜检查与宫颈活组织病理诊断结果总符合率84.6%。TCT检测和阴道镜检查对筛查女性宫颈疾病准确、可靠,有重要价值。
Objective To investigate the clinical value of thin-section liquid-based cytology and colposcopy in screening cervical lesions. Methods 5937 patients with gynecological diseases in Second People’s Hospital of Danyang City from 2010 to 2012 were enrolled in this study. Thin-section liquid-based cytology (TCT) and colposcopy were used to screen for cervical lesions. TCT was undetermined Cervical biopsy was performed in cases of ASCUS, SIL, squamous cell carcinoma (SCC) and colposcopy. Results A total of 268 TCT patients with ASCUS were diagnosed. Among them, 219 cases were pathologically diagnosed with chronic cervicitis (coincidence rate of 88.1%), 34 cases of grade Ⅰ cervical intraepithelial neoplasia (67.6% coincidence rate), 13 cases of grade Ⅲ cervical intraepithelial neoplasia Cases (76.9% compliance), cervical cancer in 2 cases (100% compliance rate). 1111 cases of abnormal colposcopy images, of which 993 cases of pathological diagnosis of chronic cervicitis (coincidence rate 96.8%), 115 cases of cervical intraepithelial neoplasia (coincidence rate 90.4%), cervical cancer in 3 cases (66.7%). Conclusion The total coincidence rate between TCT and cervical biopsy is 83.2%, and the coincidence rate between colposcopy and cervical biopsy is 84.6%. TCT test and colposcopy screening of female cervical disease is accurate, reliable, of great value.