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川附子是中医临床传统的助阳药,有温暖脾胃,补下焦阳虚之功能。本实验用羟基脲造成阳虚之小鼠,其体重25克应用川附子水溶性提取物(川附884)的用药量相当生药1.5克,每公斤体重可用至生药60克,可使“阳虚”小鼠死亡率减低,体重稍增加,更能促使特异性体液免疫提高。说明它与其它中药助阳药一样,可以使抗体形成提前。附子禀雄壮之质,有斩关夺将之气,其提取物川附884,从它壮阳的作用看来为附子主要成分之一。本品是否可用于抗肿瘤,有待进一步研究。川附844药液,虽然不能显著增加脾脏重量,但是能纠正“阳虚”小鼠的抗体滴度(表1)及促使脾脏抗体形成细胞明显增加(表2)。本实验是应用已知的核苷酸还原酶抑制剂羟基脲作为阳虚造型的药物,川附844可能激活脾脏内B 细胞中核苷酸还原酶,从而使抗体形成细胞增加。因此川附884+阳虚组小
Chuanfuzi is a traditional Chinese medicine for traditional Chinese medicine. It has a warm stomach and fills the function of Jiaoyang deficiency. In this experiment, mice with yang deficiency caused by hydroxyurea, the body weight of 25 grams of the application of Chuanxiong water-soluble extract (Chuanfu 884) the amount of crude drug 1.5 grams, 60 grams per kilogram body weight can be used to crude drugs, can make “Yang ”Mice with reduced mortality and slightly increased body weight are more likely to promote specific humoral immunity.“ It shows that it is the same as other traditional Chinese medicines to help the formation of antibodies. Aconite is a majestic and powerful creature. It has the vitality of the razor-sharp, its extract Chuan attached 884, from its aphrodisiac effect appears to be one of the main components of aconite. Whether this product can be used for anti-tumor needs further study. The Chuanfu 844 drug solution, while not significantly increasing the weight of the spleen, can correct the antibody titers in the ”yang deficiency" mice (Table 1) and promote the spleen antibody-forming cells to increase significantly (Table 2). In this experiment, hydroxyurea, a known nucleoside reductase inhibitor, was used as a yang-like drug. Chuanfu 844 may activate ribonucleotide reductase in B cells in the spleen, thus increasing the number of antibody-forming cells. Therefore, Chuan attached 884+ Yang deficiency group small