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目的:观察早期高压氧治疗(HBO)对重度颅脑外伤治疗的效果。方法:将于2015年9月至2016年1月东莞市第三人民医院收治的重度颅脑外伤患者随机均分为对照组45例和观察组45例。观察组在发生颅脑外伤的8 d~1个月内进行HBO,对照组在发生颅脑外伤的1~2个月内进行HBO。比较分析两组患者治疗前及治疗后格拉斯哥昏迷指数(GCS)及日常生活能力(ADL)评分,在患者治疗出院后的6个月后对其临床效果进行评价。结果:经治疗,所有患者的GCS及ADL评分均明显优于治疗前,且比较差异具有统计学意义(P<0.05);观察组患者的GCS及ADL评分均明显优于对照组患者同期,且比较差异具有统计学意义(P<0.05)。治疗6个月后,观察组的格拉斯哥预后分级(GOS)结果明显高于对照组,差异具有统计学意义(P<0.05)。结论:对于病情稳定的重度颅脑外伤患者来说,尽早采用HBO能提高治疗效果和改善预后。
Objective: To observe the effect of early hyperbaric oxygen therapy (HBO) on severe traumatic brain injury. Methods: Patients with severe traumatic brain injury admitted to the Third People’s Hospital of Dongguan City from September 2015 to January 2016 were randomly divided into control group (45 cases) and observation group (45 cases). HBO was observed in the observation group within 8 days to 1 month after craniocerebral trauma and in control group within 1 to 2 months after craniocerebral trauma. The Glasgow coma index (GCS) and daily living ability (ADL) scores were compared between the two groups before and after treatment, and their clinical effects were evaluated 6 months after the patients were discharged from hospital. Results: After treatment, GCS and ADL scores of all patients were significantly better than before treatment, and the difference was statistically significant (P <0.05); GCS and ADL scores of the observation group were significantly better than those of the control group, and The difference was statistically significant (P <0.05). After 6 months of treatment, Glasgow prognosis grade (GOS) in the observation group was significantly higher than that in the control group, with significant difference (P <0.05). Conclusion: HBO as early as possible can improve the therapeutic effect and improve the prognosis of stable traumatic brain injury patients.