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目的:观察支原体宫颈炎孕妇血清中IL-6水平变化,应用产后胎盘病理检查结果进行验证,求证IL-6对支原体胎盘炎的诊断价值。方法:将受试者分成宫颈支原体阴性组(正常孕妇组)、宫颈支原体阳性组。对两组孕妇血清IL-6水平进行定量检查,分别计算其平均值;对两组孕妇做产后胎盘病理检验,分别计算胎盘绒毛膜羊膜炎的发生率;对宫颈支原体阳性组做产后胎膜支原体培养,计算支原体感染胎盘炎的发生率。结果:宫颈支原体阳性组胎盘绒毛膜羊膜炎的发生率为37.25%,宫颈支原体阴性组为41.54%,两组差异无统计学意义(P>0.05),宫颈支原体阳性组中孕妇胎盘出现绒毛膜羊膜炎,胎膜支原体培养阳性,其血清IL-6明显升高,两组比较有统计学差异(P<0.05)。结论:孕妇血清中IL-6检测可以预测支原体胎盘炎。
Objective: To observe the change of serum IL-6 level in mycoplasma cervicitis pregnant women, and to verify the result of postpartum placenta pathology examination to confirm the diagnostic value of IL-6 to placenta mycoplasma. Methods: The subjects were divided into cervical mycoplasma negative group (normal pregnant women group), cervical mycoplasma positive group. The serum levels of IL-6 in the two groups of pregnant women were quantitatively examined and their mean values were calculated respectively. The placental pathology was performed on the two groups of pregnant women to calculate the incidence of placental chorioamnionitis. Incubation, calculate the incidence of mycoplasma placenta infection. Results: The incidence of placental chorioamnionitis was 37.25% in cervical mycoplasma positive group and 41.54% in cervical mycoplasma negative group, there was no significant difference between the two groups (P> 0.05). The chorioamnion Mycoplasma and Mycoplasma positive culture, the serum IL-6 was significantly increased, there was a significant difference between the two groups (P <0.05). Conclusion: IL-6 in serum of pregnant women can predict mycoplasma platitis.