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目的研究甲状腺微小乳头状癌(papillary thyroid microcarcinoma,PTMC)不同年龄段的临床病理特点。方法 PTMC病人291例,根据病人年龄,将291例病人分为年龄<35岁组、35~44岁组和≥45岁组,分析不同年龄段病人的临床病理特点。结果初诊PTMC病人291例,占同期甲状腺癌病人的63.0%,年龄21~72岁,中位年龄46岁,男女比例1∶3.3;45岁以下病人占46.0%,男性病人比例低于女性(P<0.05)。随着年龄的增大,女性病人比例、选择双侧全切或近全切病人比例,及中央组淋巴结阴性比例均明显增加(P<0.05)。35岁以下病人中,除手术方式外,PTMC病人与非PTMC病人临床病理特点相似。结论 PTMC病人年龄不同,临床病理特点存在差异。应重视年轻、男性PTMC病人的筛查及风险评估。
Objective To study the clinicopathological features of different stages of papillary thyroid microcarcinoma (PTMC). Methods A total of 291 PTMC patients were divided into two groups according to the age of their patients: 29 years old, 35-44 years old and 45 years old. The clinicopathological features of patients with different ages were analyzed. Results There were 291 newly diagnosed PTMC patients, accounting for 63.0% of the thyroid cancer patients in the same period, ranging in age from 21 to 72 years with a median age of 46 years. The ratio of male to female was 1: 3.3. The percentage of male under 45 was 46.0% <0.05). With age, the proportion of female patients, the proportion of patients who underwent bilateral total or near total resection, and the percentage of negative lymph nodes in the central group were significantly increased (P <0.05). Among the patients under the age of 35, the clinicopathological features of PTMC patients and non-PTMC patients were similar except for the surgical method. Conclusion PTMC patients have different age and clinicopathological characteristics. Attention should be paid to the screening and risk assessment of young, male PTMC patients.