With the development of Internet,e-Business has gradually become a new model for business activity,however,the security of e-Business is a major bottleneck restricting the development of e-Business.Network with virtual private network(VPN)can reduce network costs and communication costs,increase flexibility and provide safe and smooth network for the corporations that do e-Business across regions.This article introduces the definition and the technological core of VPN,and researches and analyzes the VPN application in e-commerce. With the development of Internet, e-Business has gradually become a new model for business activity, however, the security of e-Business is a major bottleneck restricting the development of e-Business.Network with virtual private network (VPN) can reduce network costs and communication costs, increase flexibility and provide safe and smooth network for the corporations that do e-Business across regions. This article introduces the definition and the technological core of VPN, and researches and analyzes the VPN application in e-commerce.