氯丙烯染毒后肌细胞的改变主要是肌丝和肌原纤维断裂或丧失,肌原纤维间隙扩大,内有许多膜性结构物,线粒体变性,糖原颗粒减少或消失,Z-盘弯曲、断裂或崩解,尤以Ⅱ型肌细胞快且重。肌卫星细胞显示核缩小,细胞浆容积增大,长度增加,平均值为35.01±12.65μm,伪足增多且长,细胞器多并发育良好。提示氯丙烯可引起神经性肌萎缩和肌卫星细胞活化。 Alzheimer’s disease after exposure to allyl chloride is mainly due to changes in muscle fibers and myofibrils rupture or loss of myofibril clearance, there are many membranous structures, mitochondrial degeneration, glycogen particles reduce or disappear, Z-disc bending, Fracture or disintegration, especially type Ⅱ muscle cells faster and heavier. Muscle satellite cells showed a reduced nucleus, increased cytoplasm volume and length, with an average of 35.01 ± 12.65 μm, an increase of pseudopodia, a long, organelle, and good development. Tip allyl chloride can cause neuromuscular atrophy and muscle satellite cell activation.