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目的:观察普拉洛芬治疗糖尿病视网膜病变激光光凝术后干眼的疗效。方法:随机选取糖尿病视网膜病变Ⅲ~Ⅳ期的48例(80眼)行视网膜激光光凝术,术后分别给予普拉洛芬(A组40眼)及妥布霉素地塞米松眼液(B组40眼)点术眼,术后3、7、14、28 d分别从自觉症状、干眼泪膜破裂时间及角膜荧光素染色评分等方面进行综合评价。结果:A组患者于用药后3 d干眼症状开始好转,于用药后7 d干眼症状改善最为明显;B组患者干眼症状没有明显改善,部分干眼症状加重。结论:普拉洛芬不仅能很好的控制激光光凝带来的炎性反应,更能有效的缓解干眼症状。
Objective: To observe the curative effect of pranoprofen on dry eye after laser photocoagulation in diabetic retinopathy. Methods: Forty-eight cases (80 eyes) of diabetic retinopathy were treated by retinal laser photocoagulation. After operation, they were given pranoprofen (group A, 40 eyes) and tobramycin dexamethasone eye drops B group 40 eyes) point surgery, respectively, 3,7,14,28 d postoperatively from the symptoms, dry tear film rupture time and corneal fluorescein staining score and other aspects of a comprehensive evaluation. Results: The symptoms of dry eye in group A began to improve after 3 days of treatment, and the symptoms of dry eye were most obvious on the 7th day after treatment. The symptoms of dry eye in group B were not significantly improved, and some dry eye symptoms were aggravated. Conclusion: Pranoprofen can not only control the inflammatory reaction caused by laser photocoagulation, but also relieve the symptoms of dry eye effectively.