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目的:探讨甲状腺乳头状癌前哨淋巴结(SLN)的检测及其对颈淋巴结转移的预测价值。方法:用术中在肿瘤周围注射亚甲蓝的方法对25例甲状腺乳头状癌患者进行SLN的临床研究,术中取蓝染淋巴结及颈清淋巴结做常规苏木精-伊红染色病理检查,并将两者进行对照,观察SLN转移对颈淋巴结转移的预测作用。结果:25例患者中22例成功地显示了SLN,成功率为88%,显示的SLN中有19例病理阳性,其中13例颈淋巴结清扫术证实有非SLN的颈淋巴结转移,5例未发现有非SLN的其他淋巴结转移,1例因自身因素未行颈淋巴结清扫术。结论:SLN检测对预测甲状腺乳头状癌淋巴结转移有重要价值。
Objective: To investigate the detection of sentinel lymph node (SLN) in papillary thyroid carcinoma and its predictive value for cervical lymph node metastasis. Methods: 25 cases of thyroid papillary carcinoma were treated with intra-operative injection of methylene blue in the study of SLN. Blue-stained lymph nodes and cervical lymph nodes were routinely processed for hematoxylin-eosin staining. And the two were compared to observe the SLN metastasis of cervical lymph node metastasis prediction. RESULTS: Twenty-two of 25 patients successfully demonstrated SLN, with a success rate of 88%, showing 19 of the SLNs pathologically positive, of which 13 had cervical lymphadenectomy confirmed non-SLN cervical lymph node metastases and 5 had not been found There were other non-SLN lymph node metastases, 1 case of cervical lymph node dissection due to their own factors. Conclusion: The detection of SLN has important value in predicting lymph node metastasis of papillary thyroid carcinoma.