近年来,国外的研究表明人乳头状瘤病毒16型、18型与人宫颈癌密切相关。在宫颈癌中可检出它们的核酸序列,在宫颈癌细胞系内可检测到它们的表达产物。为研究中国妇女子宫颈癌与HPV相互间的关系。我们用HP V18、11DNA探针检测了72例宫颈癌和一株来自中国妇女子宫颈癌细胞系中的病毒基因,并初探了它们在宿主细胞中的整合状态及其在转录水平上的表达。 In recent years, foreign studies have shown that human papillomavirus types 16 and 18 are closely related to human cervical cancer. Their nucleic acid sequences can be detected in cervical cancer, and their expression products can be detected in cervical cancer cell lines. To study the relationship between cervical cancer and HPV in Chinese women. We used HP V18,11 DNA probes to detect 72 cases of cervical cancer and one from the Chinese women’s cervical cancer cell lines in the virus genes, and to explore their integration in host cells and its expression at the transcriptional level.