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[目的]观察补阳还五汤联合西药治疗脑梗塞疗效。[方法]使用随机平行对照方法,将100例住院患者按病志号抽签法简单随机分为两组。对照组50例奥扎格雷钠40mg+0.9%生理盐水250m L,1次/d,静滴。二磷胆碱0.5g+0.9%生理盐水250m L,1次/d,静滴。治疗组50例补阳还五汤(地龙、甘草、牛膝各10g,赤芍、当归尾、川芎、红花、桃仁、丹参、鸡血藤各15g,黄芪60g;上肢偏瘫加桑枝、桂枝各10g;下肢瘫软无力加断续15g,杜仲20g;半身不遂加穿山甲、水蛭各10g;言语不利加远志10g,石菖蒲15g),1剂/d,水煎400m L,早晚口服,200m L/次;西药治疗同对照组。连续治疗90d为1疗程。观测临床症状、神经功能缺损评分、不良反应。治疗1疗程,判定疗效。[结果]治疗组基本控制10例,显效18例,有效20例,无效2例,总有效率96.00%。对照组基本控制5例,显效14例,有效15例,无效16例,总有效率68.00%。治疗组疗效优于对照组(P<0.01)。神经功能缺损评分两组均有改善(P<0.05),治疗组改善优于对照组(P<0.01)。[结论]补阳还五汤联合西药治疗脑梗塞疗效满意,无严重不良反应,值得推广。
[Objective] To observe the curative effect of Buyang Huanwu Decoction combined with western medicine on cerebral infarction. [Methods] Using randomized parallel control method, 100 inpatients were randomly divided into two groups randomly according to the random number of patients. Control group, 50 cases of ozagrel sodium 40mg + 0.9% saline 250ml, 1 times / d, intravenous infusion. Diphosphocholine 0.5g + 0.9% saline 250m L, 1 times / d, intravenous infusion. The treatment group, 50 cases of Buyang Huanwu Decoction (Radix, licorice, Achyranthes each 10g, red peony root, Angelica tail, Chuanxiong, safflower, peach kernel, Salvia Miltiorrhiza each 15g, astragalus 60g; Guizhi 10g; lower extremities weakness and weakness plus intermittent 15g, Eucommia 20g; half-body and add pangolin, leech 10g; verbal unfavorable plus Polygala 10g, Shichangpu 15g), 1 / d, decoction 400m L, morning and evening oral, 200m L / Times; Western medicine treatment with the control group. Continuous treatment of 90d for a course of treatment. Observation of clinical symptoms, neurological deficit score, adverse reactions. Treatment of a course of treatment to determine the efficacy. [Results] The treatment group basically controlled 10 cases, markedly effective in 18 cases, effective in 20 cases, ineffective in 2 cases, the total effective rate was 96.00%. In the control group, 5 cases were basically controlled, 14 cases were markedly effective, 15 cases were effective, 16 cases were ineffective, and the total effective rate was 68.00%. The treatment group than the control group (P <0.01). Neurological deficit scores were improved in both groups (P <0.05), and the treatment group improved better than the control group (P <0.01). [Conclusion] The treatment of cerebral infarction with Buyang Huanwu Decoction combined with western medicine has satisfactory curative effect and no serious adverse reactions, which deserves promotion.