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皮肤细菌感染较为常见,其程度可由轻至重度(危及生命)不等。严重的皮肤感染及其处理和预后取决于感染机理、皮肤结构和致感染微生物。原发性皮肤感染的病因是微生物由表皮、细微裂口侵入或经血流扩散。继发感染来自创伤、烧伤或手术伤口,有关皮肤软组织感染亦进行了讨论。对病因、细菌学因素和皮肤感染的处理进行了研究,尤其着重于脓皮病、糖尿病患者的足部感染和坏死性软组织感染。抗生素的选择在很大程度上取决于感染菌种或抗菌类型,在坏死性软组织感染,其治疗依赖于外科手术。在上述情况和某些晚期皮肤感染,应采用非肠道抗生素。本文讨论替卡西林二钠与克拉维钾联合应用的效果。
Skin bacterial infections are more common and vary in severity from mild to severe (life-threatening). Severe skin infections and their management and prognosis depend on the mechanism of infection, the structure of the skin and the microorganisms causing infection. The cause of primary skin infections is the invasion of microbes from the epidermis, the tiny nicks, or the spread of blood flow. Secondary infection comes from wounds, burns or surgical wounds. Skin and soft tissue infections are also discussed. The etiology, bacteriological factors, and treatment of skin infections were studied, with particular emphasis on pyoderma, foot infections in diabetic patients, and necrotizing soft tissue infections. The choice of antibiotic depends largely on the type of infection or the type of antibacterial. In the case of necrotizing soft tissue infections, the treatment depends on the surgical procedure. In these cases and some advanced skin infections, should be used parenteral antibiotics. This article discusses the effect of ticarcillin disodium and clavulanate in combination.