玻璃体血管新生多继发于糖尿病视网膜病变、视网膜中央静脉阻塞、白塞氏病等眼内病变,是引起玻璃体出血和视网膜脱离的眼部病变的重症合并症。血管新生本来是作为机体的创伤愈合机制之一而发生的,但在眼球,由于玻璃体内血管新生,却可有碍眼内组织的透明性。玻璃体血管新生的好发部位是视神经乳头和睫状体扁平部,特别后者尤其好发血管新生,其原因是由于在睫状体扁平部和视网膜锯齿缘的移行部存在着联络玻璃体侧和脉络膜侧的潜在通路。视网膜锯齿缘相当于胎生期眼杯的尖端部,构成葡萄膜血管和晶状体血管膜的联系路。眼杯的尖端部延伸形成睫状体上皮层及虹膜上皮层。开始,这些上皮细胞把存在于眼杯尖端的血管拉进来并延伸到角膜 Vitreous angiogenesis and more secondary to diabetic retinopathy, central retinal vein occlusion, Behcet’s disease and other intraocular lesions, is caused by vitreous hemorrhage and retinal detachment of the ocular lesions of severe complications. Angiogenesis originally occurred as one of the body’s mechanisms of wound healing, but in the eye, due to intravitreal angiogenesis, it can hinder the transparency of intraocular tissue. The predilection sites for vitreous angiogenesis are the optic nerve head and the ciliary body flattened part, especially the latter are predominantly angiogenic, due to the presence of a connective vitreous side and a choroid in the ciliary body flattened part and retinal jagged margin Side of the potential path. Retinal jagged edge is equivalent to the tip of the eye cup of viviparous period, the formation of uveal vessels and lens vascular membrane contact. The tip of the eye cup extends to form the ciliary epithelium and iris epithelium. Initially, these epithelial cells pull the blood vessels that exist at the tip of the eye cup and extend to the cornea