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对湖南长沙市４所医院中的２００对Ⅱ型糖尿病（Ｎｏｎ－Ｉｎｓｕｌｉｎ－ＩｎｄｅｐｅｎｄｅｎｔＤｉａｂｅｔｅｓＭｅｌｉｔｕｓ，ＮＩＤ－ＤＭ）和非Ⅱ型糖尿病进行１∶１病例对照研究，调查其少儿阶段的暴露情况，采用条件Ｌｏｇｉｓｔｉｃ回归分析。结果显示：ＮＩＤＤＭ的早期危险因素有：油炸食物（Ｂｉ＝２．４９５，ＯＲ＝１２．１２２）、甜食（Ｂｉ＝２．３６９，ＯＲ＝１０．６８７）、腮腺炎史（Ｂｉ＝２．２３９，ＯＲ＝９．３００）、饥饿（Ｂｉ＝１．０６５，ＯＲ＝２．９０１）以及暴饮暴食（Ｂｉ＝０．８４９，ＯＲ＝２．３７７）；而蔬菜（Ｂｉ＝－２．３１３，ＯＲ＝０．１００）对ＮＩＤＤＭ有保护作用。提示少儿阶段的生活饮食因素和病毒感染很可能与Ⅱ型糖尿病的发生有密切关系，因此，ＮＩＤＤＭ的预防要从小抓起，提倡少儿阶段合理平衡饮食，积极预防病毒感染，是早期预防Ⅱ型糖尿病的重要对策。
A case-control study of 200 cases of non-insulin-independent diabetes mellitus (NID-DM) and non-type II diabetes in 4 hospitals in Changsha, Hunan Province was conducted to investigate the infancy in children. The conditional Logistic regression analysis. The results showed that the early risk factors of NIDDM were fried food (Bi = 2.495, OR = 12.122), sweet food (Bi = 2.369, OR = 10.687) and mumps history (Bi = 2. (Bi = 0.849, OR = 2.377); while vegetables (Bi = -2.313, OR = 9.300) , OR = 0.100) have protective effect on NIDDM. Tip children’s stage of life and diet factors and viral infection is likely to be closely related with the occurrence of type II diabetes, therefore, prevention of NIDDM should start small, advocate a reasonable balance of children’s diet, and actively prevent the virus infection is early prevention of type 2 diabetes Important countermeasure