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目的:探讨喜炎平注射液辅助常规治疗急性支气管肺炎患者的疗效效果及对血清IL-4、IFN-γ水平的影响。方法:回顾性分析60例急性支气管肺炎患者临床资料按照治疗方式分为2组,30位患者采用常规治疗(对照组),30位给予喜炎平注射液联合常规治疗(研究组)。将两组患者临床疗效、临床症状体征改善情况及血清IL-4、IFN-γ水平进行对比。结果:研究组患者临床有效率96.66%较对照组80.00%显著要高(P<0.05)。研究组患者临床症状消失时间较对照组均短(P<0.05)。两组患者血清IL-4水平降低,IFN-γ水平升高,且研究组较对照组改变明显(P>0.05)。结论:急性支气管肺炎患者治疗中选择喜炎平注射液辅助常规治疗可显著提高患者治疗效果,改善血清IL-4、IFN-γ水平,缩短患者恢复时间。
Objective: To investigate the therapeutic effect of Xiyanping injection in adjuvant routine treatment of acute bronchopneumonia and its effect on the level of serum IL-4 and IFN-γ. Methods: The clinical data of 60 patients with acute bronchopneumonia were retrospectively analyzed. The clinical data were divided into two groups according to the treatment method. Thirty patients were treated with conventional therapy (control group) and 30 were treated with Xiyanping injection combined with conventional therapy (study group). The clinical efficacy, clinical signs and symptoms and serum IL-4, IFN-γ levels were compared between the two groups. Results: The clinical effective rate in study group was significantly higher than that in control group (96.66% vs 80.00%, P <0.05). The disappearance time of clinical symptoms in study group was shorter than that in control group (P <0.05). Serum levels of IL-4 and IFN-γ in the two groups were significantly lower than those in the control group (P> 0.05). Conclusion: The treatment of acute bronchopneumonia patients selected Xiyanping injection adjuvant conventional therapy can significantly improve patient outcomes, improve serum levels of IL-4, IFN-γ, shorten the recovery time of patients.