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冒烟性白血病系急性非淋巴细胞白血病的一个亚型,其特征为骨髓内白血病性原始细胞<50％,故又称低原始细胞性白血病。有别于骨髓增生异常综合征(MDS)和白血病前期。多发于老年人,对细胞毒剂化疗药物反应差。作者为了得到该病自然的临床资料,于24例初诊的冒烟性白血病仅采用一般性支持性措施。骨髓原始细胞绝对数由骨髓活检切片中总的细胞成分(％)与原始细胞分类(％)相乘而得。无或仅有少数嗜阿尼林篮颗粒的原粒细胞超过骨髓原始细胞的30％,则符合急粒细胞白血病的诊断标准。除原始细胞绝对数之外,识别白血病细胞的辅助特征为:(1)明显的、细胞化学可证实的Auer小体;(2)形态类似的原始细胞呈局灶性聚集,称之为“原始细胞丛”;(3)
Smoky leukemia is a subtype of acute non-lymphocytic leukemia characterized by <50% of myeloid leukemic blasts and is also known as low-grade blaukemia. Unlike myelodysplastic syndrome (MDS) and pre-leukemia. Occur in the elderly, poor response to cytotoxic chemotherapy drugs. In order to get the natural clinical data of the disease, the authors used only general supportive measures in 24 newly diagnosed smokers with leukemia. The absolute number of bone marrow blasts is obtained by multiplying the total cellular fraction (%) in the bone marrow biopsy and the original cell classification (%). None or only a few addicted baskets of anilin granules exceeded 30% of myeloid blasts, which met the diagnostic criteria for acute myeloid leukemia. In addition to the absolute number of blasts, the ancillary traits for identifying leukemia cells are: (1) significant, cytochemically-validable Auer bodies; (2) focal accumulation of morphologically similar primitive cells, termed “primitive Cell bundle ”; (3)