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本文报告了15例小儿高白细胞急性白血病病例,发现本组病人除具备一般急性白血病的特点外,还常伴有高粘滞血症的临床特征。本组采用两种化疗作用强弱不同的方案进行开始诱导缓解治疗高白细胞急性白血病,对其转归进行对比,认为对此类病在进行诱导化疗的初期,应选用化疗作用较缓和的方案,待化疗使周围血中的白细胞下降到一定程度后,再用一般的常规化疗方案,避免在诱导缓解一开始用强化疗所致的许多与白细胞过多有关的并发症,以提高此类病人的缓解率。
This article reports 15 cases of children with high white blood cell acute leukemia and found that patients in addition to the general characteristics of acute leukemia, but also often accompanied by clinical features of hyperviscosity. In this study, we used two different chemotherapy regimens to start induction and remission treatment of high leukemia acute leukemia and compared their prognosis. It is suggested that the chemo-chemotherapy should be used more moderately in the initial stage of such chemotherapy, Chemotherapy to peripheral blood leukocytes down to a certain extent, and then use the conventional chemotherapy regimen to avoid the beginning of induction of remission with chemotherapy and many of the complications associated with leukocytosis to improve such patients Mitigation rate.