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皮质醇症的临床表现系糖皮质激素分泌过多所致。导致分泌过多的因素有:(1)为治疗而应用过置的促肾上腺皮质激素(ACTH)或糖皮质激素;(2)肾上腺良性或恶性肿瘤分泌过多的皮质激素;(3)异位 ACTH 综合症;(4)垂体分泌过多的 ACTH 使双侧肾上腺皮质增生。临床上以垂体病变最多见。Orth 等认为此症的埋想治疗须达到下列四个目的:(1)临床及生化提示皮质激素已降至正常水平;(2)切除分泌激素的肿瘤;(3)无肾上腺或垂体永久性功能不足;
The clinical manifestations of cortisol are due to excessive secretion of glucocorticoids. Factors leading to hypersecretion are: (1) the use of adrenocorticotropic hormone (ACTH) or glucocorticoids for treatment; (2) the secretion of corticosteroids in benign or malignant adrenal glands; (3) ectopic ACTH syndrome; (4) pituitary hypersecretion of ACTH hyperplasia of the adrenal cortex. The most common pituitary lesions are clinically seen. Orth et al believe that the burying treatment of this disease must achieve the following four purposes: (1) clinical and biochemical findings that corticosteroids have been reduced to normal levels; (2) excision of hormones secreting hormones; (3) no adrenal or pituitary permanent function insufficient;