患男婴,三个月。因进行性喂养困难,消瘦两月余入院.生后20天时出现鼻塞,吃奶呛咳伴喘憋,青紫,腹胀,哭声弱,少动,进行性消瘦。在家曾口服乳酶生等无效。第二胎第二产,出生体重3.5kg。其母孕早期曾高热达40℃.诊断服药不祥。查体 T:36℃,P100次/分,体重3.5kg,发育营养极差,神志清,精神差,表情淡漠,反应差,哭无声,呼吸困难。皮下脂肪消失,全身皮肤粗糙,弹性差, Baby boy, three months. Due to progressive feeding difficulties, weight loss more than two months admitted to hospital after 20 days after birth stuffy nose, numbness cough with wheezing, bruising, abdominal distension, crying weak, less moving, progressive weight loss. At home had oral lactase Health and other invalid. Second child second production, birth weight 3.5kg. The mother had a high fever in early pregnancy up to 40 ° C. Diagnostic medication ominous. Examination T: 36 ℃, P100 beats / min, body weight 3.5kg, very poor nutritional development, consciousness, poor spirit, apathy, poor response, crying silent, breathing difficulties. Subcutaneous fat disappears, the body rough skin, poor elasticity,