目的阐明硬、软蒺藜两者药效学关系。方法选择抗血栓、镇痛、抗炎、抗惊厥、安神等指标对硬、软蒺藜水提物进行比较药效学研究。结果二者均有显著的抗血栓及镇痛作用，对慢性炎症过程亦呈现明显的对抗作用，均无对抗戊四唑诱发惊厥的作用，亦未显示有效的安神催眠作用。结论硬、软蒺藜在诸药理作用方面功效相似。 Objective To clarify the pharmacodynamic relationship between hard and soft palate. Methods The anti-thrombotic, analgesic, anti-inflammatory, anti-convulsant, and soothe the nerves were selected to compare the pharmacodynamics of hard and soft water extracts. Results Both had significant anti-thrombotic and analgesic effects and showed significant antagonistic effects on chronic inflammatory processes. None of them had effects on pentylenetetrazole-induced seizures, nor did they show effective soothing and hypnotic effects. Conclusion Hard and soft palate have similar efficacy in pharmacological effects.