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我们自1987年12月以来,对1496例镜检中发生痉挛性腹痛的85例应用硝苯吡啶含服,疗效满意。病例选择选择镜检过程中镜下有肠管痉挛性收缩致剧烈腹痛不能耐受进一步检查者。方法当即给予硝苯吡啶15mg嚼碎后舌下含服,暂停5分钟后再予进镜,症状不缓解者再加用硝苯吡啶5 mg含服,同时延长暂停进镜时间5分钟。记录症状减轻程度。结果用药后显效(症状消失,镜下见痉挛解除)63例(74.1%),有效(症状明显减轻,镜下痉挛解除)16例(18.9%),无效(症状无减轻或略有减轻,但镜下痉挛无解除,仍不能耐受检查者)6例(7%),总有效率93%,其中有效及无效者均经加服硝苯吡啶5 mg含服。讨论硝苯吡啶为钙离子拮抗剂,而在胃肠道
We since December 1987, 1496 cases of microscopic examination of spasmodic abdominal pain in 85 patients treated with nifedipine, the effect is satisfactory. Case Selection Select microscopic examination during the spasm of the spasm of the spleen to severe abdominal pain can not tolerate further examination. Methods Immediate nifedipine 15mg chewed sublingual, suspended for 5 minutes before entering the mirror, the symptoms were not relieved plus nifedipine 5mg service, while prolonging the time into the mirror for 5 minutes to suspend. Record the degree of symptom relief. Results Sixty-three patients (74.1%) had effective (symptom relieved, microscopic spasm was relieved), 16 patients (18.9%) were ineffective (no or slight alleviation of symptoms, 6 cases (7%) had a total effective rate of 93%. Among them, effective and ineffective were given 5 mg nifedipine. Discussion Nifedipine is a calcium-channel antagonist, whereas in the gastrointestinal tract