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由于人绒毛膜促性腺激素(hCG)是妊娠早期时滋养层最早分泌产物之一,它仅作用于卵巢的黄体细胞以合成孕酮,是维持早期妊娠的关键因素。如果设法干扰其作用,就能达到终止早期妊娠的效果。因此,hCG被首先确定为一种潜在的、有效的避孕疫苗。 hCG是分子量为38KD的糖蛋白,含有30％的糖。其结构及其氨基酸序列已经清楚。由α和β两个亚单位组成。α亚单位与三种垂体激素(促甲状腺素TSH;
Since human chorionic gonadotropin (hCG) is one of the earliest trophoblast secretion products during early gestation, it only acts on luteal cells of the ovary to synthesize progesterone, which is the key factor to maintain early pregnancy. If you try to interfere with its role, you can achieve the effect of termination of early pregnancy. Therefore, hCG was first identified as a potential and effective contraceptive vaccine. hCG is a glycoprotein with a molecular weight of 38 kD, containing 30% sugar. Its structure and amino acid sequence has been clear. By α and β two subunits. α subunit and three pituitary hormones (thyrotropin TSH;