Wetland is one of the richest biodiversity areas in the earth. The main purpose of establishing wetland protected area is to protect biodiversity, and the protection of ecosystem diversity and landscape diversity is the key to protect biodiversity. In order to protect regional ecosystem and landscape, it is a good way to establish wetland comprehensive protected area which connected wetland nature reserves by habitat corridors. The Sanjiang Plain as a study area, its landscape evaluation index system on wetland protected area was studied, and some problems on landscape planning and ecology construction were further approached in this paper. It showed that establishing wetland comprehensive protected area is very important to protect regional wetlands, to maintain ecological balance,and to improve the sustainable development of agriculture and industry in this region.