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目的探讨孤独症谱系障碍(ASD)患者和食物不耐受(食物敏感)二者之间的关系。方法对30例ASD患者、30例精神发育迟滞的患者和30例正常对照组进行食物不耐受的检测。结果 ASD组食物不耐受的阳性发生率为46.7%,显著高于精神发育迟滞组的16.7%(χ2=4.08,P<0.05)和正常组的13.3%(χ2=4.83,P<0.05);食物不耐受阳性的14例ASD患者的孤独症行为量表(ABC)得分为较阴性者的显著为高(t=4.23,P<0.01)。结论 ASD与食物不耐受有关,食物不耐受阳性的ASD患者症状较严重。
Objective To investigate the relationship between patients with autism spectrum disorder (ASD) and food intolerance (food-sensitivity). Methods Food intolerance was measured in 30 ASD patients, 30 patients with mental retardation and 30 normal controls. Results The positive rate of food intolerance in ASD group was 46.7%, significantly higher than that in mental retardation group (χ2 = 4.08, P <0.05) and in normal group (13.3%, χ2 = 4.83, P <0.05). The scores of autistic behavior disorder (ABC) in 14 ASD patients with food intolerance were significantly higher than those with negative (t = 4.23, P <0.01). Conclusions ASD is associated with food intolerance and symptoms are more severe in ASD patients with food intolerance.