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目的:探讨限制性液体复苏与常规液体复苏对失血性休克患者死亡率、凝血功能及并发症的影响。方法:选取失血性休克患者100例,随机分为限制组(n=55)和常规组(n=45),其中限制组采用限制性液体复苏抗休克,而常规组采用常规液体复苏。比较两组患者输液量及死亡率、血压与检验指标、并发症发生率。结果:与常规组相比,限制组患者输液量较少,死亡率较低,痊愈率较高,差异有统计学意义(P<0.05)。与常规组相比,限制组患者平均动脉压、碱剩余明显较低,血红蛋白、血小板、红细胞比容明显较高,凝血酶原时间明显较短,差异有统计学意义(P<0.001)。与常规组相比,限制组患者急性呼吸窘迫综合征、多器官功能障碍综合征发生率较低,差异有统计学意义(P<0.05)。结论:限制性液体复苏为失血性休克患者赢得更多后续急诊手术止血时间,能降低患者死亡率和并发症如急性呼吸窘迫综合征、多器官功能障碍综合征的发生率。
Objective: To investigate the effects of restrictive fluid resuscitation and conventional fluid resuscitation on mortality, coagulation and complications in patients with hemorrhagic shock. Methods: One hundred patients with hemorrhagic shock were randomly divided into two groups: control group (n = 55) and control group (n = 45). Restrictive fluid resuscitation was used in the control group and conventional fluid resuscitation was performed in the control group. The two groups of patients were compared transfusion and mortality, blood pressure and test indicators, the incidence of complications. Results: Compared with the conventional group, the patients in the restricted group had less transfusion, lower mortality and higher cure rate, with a significant difference (P <0.05). Compared with the conventional group, the average arterial pressure, the excess of base in the patients in the restricted group were significantly lower, the hemoglobin, platelet and hematocrit were significantly higher, and the prothrombin time was significantly shorter (P <0.001). Compared with the conventional group, the incidence rate of acute respiratory distress syndrome and multiple organ dysfunction syndrome in the restricted group patients was lower, the difference was statistically significant (P <0.05). CONCLUSIONS: Restrictive fluid resuscitation won more follow-up of emergency surgery for patients with hemorrhagic shock and reduced mortality and complications such as acute respiratory distress syndrome and multiple organ dysfunction syndrome.