贵阳市妇幼保健院是全国出生缺陷监测网边远地区大城市网点的监测医院 ,该文报告近 6年对16988例围产儿进行出生缺陷监测的结果 :发现先天畸形 14 5例 ,男 68例、女 77例 ,检出率 0 85 % ,其中单发畸形10 5例 ,多发畸形 40例。检出畸形 49种 ,189人次 ,先天性心脏病位居第 1位。产前检出 46例占总检出人数的31 70 % ,死胎、死产及 7d内死亡 111例 ,存活 34例 ,存活畸形种类 ,先天性心脏病居第 1位 ,分娩母亲 <2 0岁和≥ 35岁孕妇分娩先天畸形儿的几率较高分别为 1 69%和 1 5 2 % ,在≥ 2 0岁和≤ 35岁间的孕妇分娩先天畸形儿的几率相对较低≤ 1 0 0 % ,其中 2 5～ 30岁组最低为 0 73%。同时介绍了对先天缺陷采取的三级预防及干预性措施 Guiyang City Maternal and Child Health Hospital is the National Birth Defects Monitoring Network outlying areas metropolitan network of monitoring hospitals, the paper reports the past 6 years on the 16988 cases of perinatal birth defects monitoring results: found congenital malformations 14 cases, 68 males and females 77 cases, the detection rate of 0 85%, of which 105 cases of single malformations, multiple deformities in 40 cases. 49 kinds of abnormalities were detected, 189 person-times, congenital heart disease ranked first. Prenatal detection of 46 cases accounted for 31 70% of the total number of detected, stillbirth, stillbirth and 111 cases of death within 7d, 34 cases of survival, survival deformity, congenital heart disease ranked No. 1, mother of delivery <20 And those who were ≥ 35 years old had a higher incidence of congenital malformations of children with childbirth of 1 69% and 15 2% respectively. The incidence of congenital malformations in pregnant women ≥ 20 years and ≤ 35 years old was relatively low ≤ 1 0 0% , Of which the lowest in 25-30 age group was 0 73%. At the same time introduced the tertiary defect prevention and intervention measures taken