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目的总结药物联合内镜治疗食管静脉曲张破裂出血的临床价值。方法289例确诊为肝硬化食管静脉曲张活动性出血或有新近出血征象患者,内镜下进行药物联合套扎、硬化治疗,术后观察疗效及随访。结果289例患者最初均止血成功,急症止血率达100%,早期再发生出血26例,再出血率为8.9%,曲张静脉消失率87.5%。曲张静脉复发时间多在曲张静脉根除后5月～18月,复发率14.5%。结论药物联合内镜治疗是治疗急性食管静脉曲张破裂出血有效的治疗方法之一,长期药物治疗可降低再出血率和病死率。
Objective To summarize the clinical value of drug combination endoscopy in the treatment of esophageal variceal bleeding. Methods 289 patients diagnosed as active cirrhosis esophageal variceal bleeding or recent signs of bleeding in patients undergoing endoscopic ligation, sclerotherapy, postoperative efficacy and follow-up. Results All 289 patients were initially treated with hemostasis. The rate of hemostasis in emergency was 100%. There were 26 cases of early rebleeding, 8.9% of rebleeding and 87.5% of varicose vein disappearance. Varicose vein recurrence time and more in varicose vein eradication after May to 18 months, the recurrence rate was 14.5%. Conclusion The drug combination endoscopy is one of the effective treatments for the treatment of acute esophageal variceal bleeding. Long-term drug treatment can reduce the rate of rebleeding and mortality.