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药物缓控释体系的研究在材料化学与生物医药领域备受关注。凝胶体系由于其良好的结构可控性、生物相容性和环境响应性等特点,使其成为一类重要的药物缓控释载体。刺激响应性是凝胶药物控释体系有效应用的关键,基于温度、pH值、磁场、光和葡萄糖浓度等环境因素,对凝胶体系在药物控释领域中的研究进展进行了总结与归纳,为环境响应性凝胶的开发与应用提供理论基础。
Drug controlled release system research in the field of materials chemistry and biomedicine concern. Due to its good structural controllability, biocompatibility and environmental responsiveness, gel system has become an important class of drug controlled release carriers. The stimuli responsiveness is the key to the effective application of gel controlled drug delivery system. Based on the environmental factors such as temperature, pH value, magnetic field, light and glucose concentration, the research progress of the gel system in the field of drug controlled release is summarized and summarized. Provide a theoretical basis for the development and application of environment-responsive gels.