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最近发现在。干扰素（IFN-α）治疗的慢性病毒性肝炎病人和毛细胞白血病病人中，有胰岛素依赖型糖尿病散发存在。为证实用IFN-α治疗慢性病毒性肝炎病人是否诱发抗β细胞抗原的自身免疫反应，检测了IFN－α治疗前和治疗过程中病人血清中的胰岛细胞抗体（ICA）和胰岛素自身抗体
Recently found in. Interferon (IFN-α) -treated patients with chronic viral hepatitis and hairy cell leukemia, insulin-dependent diabetes existance exists. To demonstrate whether autoimmune responses to anti-beta-cell antigens are induced in patients with chronic viral hepatitis treated with IFN-alpha, the islet cell antibody (ICA) and insulin autoantibodies in patient serum before and during IFN-alpha treatment