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成年人胃食管反流病发病率约为 10 %左右 ,常表现为烧心感。质子泵抑制剂 (PPI)可有效治愈反流性食管炎 ,且无论在治愈糜烂或缓解相关症状方面都明显优于H2 受体拮抗剂。抑酸强度与食管炎治愈率有明显相关性。目前在英国获准上市的治疗反流性食管炎的PPI包括 :奥美拉唑(
The incidence of gastroesophageal reflux disease in adults is about 10%, often manifested as heartburn. Proton pump inhibitors (PPIs) are effective in treating reflux esophagitis and are clearly superior to H2 receptor antagonists in terms of healing erosion or alleviating the associated symptoms. Acid suppression and esophagitis cure rate was significantly correlated. PPIs currently approved for the treatment of reflux esophagitis in the UK include: omeprazole