目的 :探讨治疗侵入颅内的鼻腔、鼻窦内翻性乳头状瘤 (NIP)的方法。方法 :9例NIP患者均行手术治疗。 6例侵犯前颅窝硬脑膜及脑组织的较大肿瘤行颅面联合进路或经颅进路肿物切除术 ,3例侵犯颅内较小的肿瘤经额筛窦径路切除。对术中颅底骨质缺损或硬脑膜切除者可同步修补。 5例术后病理证实癌变者均补充放射治疗。结果 :7例随访 3～ 13年 ,无一例复发。结论 :对于侵入颅内的NIP应充分考虑到其恶变的可能性 ,可根据肿瘤大小、侵犯范围行颅面联合进路或经额窦内板切除术 ,达到根治性切除的目的 Objective: To explore the method of treating nasal and sinus inverted papilloma (NIP) invading the brain. Methods: Nine patients with NIP underwent surgical treatment. 6 cases of invasion of the anterior fossa dura and brain tissue larger craniofacial approach or transcranial approach tumor resection, 3 cases of invasion of smaller intracranial tumors by the amount of ethmoid sinus pathology. Intraoperative skull base defect or dura excision can be synchronized repair. Five cases of pathologically confirmed cancers were supplemented with radiotherapy. Results: 7 cases were followed up for 3 ~ 13 years, no case of recurrence. Conclusion: For the invasion of intracranial NIP should take into account the possibility of malignant transformation, according to the size of the tumor, the scope of violations of craniofacial joint approach or frontal sinus ligation, to achieve the purpose of radical resection