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目的:探讨野芭蕉治疗高血压左心室肥厚(LVH)患者氧化应激功能紊乱的效果。方法:选取90例LVH患者随机分为治疗1组和治疗2组两组,每组45例,治疗2组给常规西药治疗,治疗1组用西药加野芭蕉中药治疗,于治疗前后检测患者的超氧化物歧化酶(SOD)、过氧化氢酶(CAT)、谷胱甘肽过氧化物酶(GSH-PX)、丙二醛(MDA)水平,并与42例健康对照组比较。结果:治疗1组治疗前血清SOD、CAT和GSH-PX均值低于对照组MDA均值高于健康对照组(P<0.01),治疗后血清SOD、CAT和GSH-PX水平提高(P<0.01,P<0.05),MDA下降(P<0.05)。结论:野芭蕉通络汤联合西药治疗LVH,对患者的氧化应激功能紊乱有确切的纠正作用。
Objective: To investigate the effect of wild banana on oxidative stress disorder in patients with hypertensive left ventricular hypertrophy (LVH). Methods: Ninety patients with LVH were randomly divided into treatment group 1 and treatment group 2, with 45 cases in each group. The treatment group 2 was given conventional Western medicine. The treatment group 1 was treated with western medicine plus wild banana Chinese medicine, and the patients’ (SOD), catalase (CAT), glutathione peroxidase (GSH-PX) and malondialdehyde (MDA) levels were measured and compared with 42 healthy controls. Results: The average serum SOD, CAT and GSH-PX in the treatment group 1 before treatment were lower than those in the control group (P <0.01), and the levels of SOD, CAT and GSH-PX in the treatment group 1 were significantly increased after treatment P <0.05), MDA decreased (P <0.05). Conclusion: Wild Basho Tongluo Decoction combined with Western medicine in the treatment of LVH, the patient’s oxidative stress disorder has an exact role in correcting.