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无环鸟苷(Acyclovir)是一种新一代的选择性抗病毒剂。它作为抗疱疹剂,其选择性主要建立在对一种或多种病毒酶的特异性作用的基础上,能高度特异性地抑制疱疹病毒的复制。静注无环鸟苷双盲安慰剂对照试验表明,无环鸟苷对免疫缺陷病人的粘膜、皮肤疱疹、原发性生殖器疱疹及急性带状疱疹具有确切疗效。对患单纯疱疹的免疫缺陷病人,当每8小时以250 mg/m~2剂量静注(750mg/
Acyclovir is a new generation of selective antiviral. It acts as an anti-herpes agent and its selectivity is based primarily on the specific effects on one or more viral enzymes and inhibits the herpes virus replication with a high degree of specificity. A double-blind, placebo-controlled trial of intravenous acyclovir demonstrated that acyclovir has the exact effect on mucosa, skin herpes, primary genital herpes and acute shingles in immunocompromised patients. In patients with herpes simplex immunodeficiency, when every 8 hours at a dose of 250 mg / m ~ 2 intravenously (750mg /