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为探讨QTc离散度(QTcd)与心肌缺血和冠状动脉(简称冠脉)病变程度的关系,分析28例冠脉正常和57例冠心病患者12导联心电图的QTcd。结果示:冠心病组QTcd较冠脉正常组显著增大(46.7±12.6msvs26.3±10.9ms,P<0.01);不稳定型心绞痛QTcd明显大于稳定型心绞痛者(54.6±13.7msvs42.3±14.1ms,P<0.05);双支病变与单支病变以及三支病变与双支病变相比,QTcd均有显著增大(48.7±13.2msvs35.7±11.9ms及59.6±15.1msvs48.7±13.2ms,P均<0.05)。提示心肌缺血是引起冠心病患者QTcd增大的主要原因之一,QTcd的变化对于判断心肌缺血和冠脉病变程度有一定价值。
To investigate the relationship between QTc Dispersion (QTcd) and the degree of myocardial ischemia and coronary artery disease (CAB), the QTcd of 12-lead electrocardiogram in 28 patients with normal coronary artery and 57 patients with coronary heart disease was analyzed. The results showed that: QTcd in coronary heart disease group was significantly higher than that in normal coronary artery group (46.7 ± 12.6ms vs26.3 ± 10.9ms, P <0.01); QTcd in unstable angina was significantly higher than that in stable angina pectoris .6 ± 13.7ms vs42.3 ± 14.1ms, P <0.05). Compared with single-vessel disease and double-vessel disease, double-vessel disease showed a significant increase in QTcd (48.7 ± 13 .2msvs35.7 ± 11.9ms and 59.6 ± 15.1msvs48.7 ± 13.2ms, P <0.05). It is suggested that myocardial ischemia is one of the main causes of QTcd increase in patients with coronary heart disease. The change of QTcd has some value in judging the degree of myocardial ischemia and coronary artery disease.