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目的检索并分析截至2016年2月耐碳青霉烯类鲍曼不动杆菌的研究的相关文献,明确耐碳青霉烯类鲍曼不动杆菌的目前研究概况,为耐碳青霉烯类鲍曼不动杆菌的研究领域或临床用药提供一定参考。方法计算机检索WEB OF SCIENCE数据库,采用文献计量学方法,对纳入文献的年代、第一作者及研究机构、来源期刊分布情况、研究内容、中国发表文献情况等进行统计分析。结果共检索出文献539篇,计算机去重后共531篇。文献数量总体呈逐年上升趋势,至2015年达峰值72篇。研究内容分析包括耐碳青霉烯类鲍曼不动杆菌感染的流行病学特点,耐药机制,体外研究或动物试验,临床治疗药物间的相互作用等。结论人们对耐碳青霉烯类鲍曼不动杆菌的研究愈发增多,对其流行病学特点的研究已相对透彻,但耐碳青霉烯类鲍曼不动杆菌的耐药机制及感染的治疗仍是目前研究的两大热点。
OBJECTIVE To search and analyze the related literature on the research of carbapenem-resistant Acinetobacter baumannii up to February 2016. The current research status of resistant carbapenem-resistant Acinetobacter baumannii is defined as carbapenem- Acinetobacter Bauhinia research areas or clinical medication provide some reference. Methods The WEB OF SCIENCE database was retrieved by computer, and the bibliometrics method was used to make a statistical analysis on the age, authors and research institutes, the distribution of the source journals, the content of the research and the published documents in China. Results A total of 539 articles were retrieved and 531 articles were retrieved after the computer was removed. The overall number of articles shows an upward trend year by year, reaching a peak of 72 in 2015. The content of the study includes the epidemiological characteristics of resistance to carbapenem-resistant Acinetobacter baumannii, the mechanism of drug resistance, in vitro studies or animal experiments, and the interaction between clinical treatments. Conclusions The research on carbapenem-resistant Acinetobacter baumannii has been more and more widely studied, and its epidemiological characteristics have been studied relatively thoroughly. However, the resistance mechanism and infection of carbapenem-resistant Acinetobacter baumannii The treatment is still the two hot spots of the current study.