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目的:通过对本院社区获得性肺炎(CAP)患者抗菌药物使用情况的调查分析和合理性研究,提高医院合理用药水平,增强临床医生合理用药意识。方法:采用回顾性调查方法,统计某院2011年1月至6月196例CAP住院患者的使用抗菌药物的品种、使用频率、用药频度(DDDS)、药物利用度(DUI)、首剂抗菌药物、联合用药等指标,并对其进行比较分析。结果:抗菌药物使用率为100%,而使用品种为52种,DDDS最高的抗菌药物为注射用头孢地嗪钠,DUI为0.9~1.1有12种抗菌药物。结论:CAP抗菌药物使用以β-内酰胺类、喹诺酮类或两者联合用药为主,使用剂量相对较为谨慎,存在个别的不合理现象,应加强对抗菌药物合理利用的指导,以提高临床治疗水平。
OBJECTIVE: To investigate and analyze the rational use of antibacterials in patients with community-acquired pneumonia (CAP) in our hospital to improve the rational use of drugs in hospitals and enhance the awareness of rational use of drugs by clinicians. Methods: A retrospective survey was conducted to determine the frequency of antibiotics, frequency of use, frequency of drug use (DDDS), drug utilization (DUI), antibacterial activity of the first dose of antibacterials in 196 CAP inpatients from January to June 2011 in a hospital. Drugs, combined medication and other indicators, and its comparative analysis. Results: The antibacterial drug use rate was 100%, while the use of 52 varieties, the highest DDDS antibacterial drug cefodizime sodium for injection, DUI 0.9 to 1.1 with 12 kinds of antibacterial drugs. Conclusion: The use of antibacterials for CAP is based on the combination of β-lactams, quinolones or both. The dosage is relatively cautious. There are some unreasonable phenomena. Therefore, it is necessary to strengthen the guidance on the rational use of antibacterials in order to improve the clinical treatment Level.