POEMS 综合征是一多系统病变,常伴浆细胞瘤。临床表现复杂易误诊。本文报告1例。患者男,54岁。因发热咳嗽、咯暗红色痰,每日量约100毫升一个月,于1993年2月28日入院。用青霉素治疗无好转。一周前出现胸闷、气短、不能平卧。外院胸穿为血性胸水。并出现双下肢浮肿,间断排肉眼血尿。查体:T 38℃,P 104次/分,R 25次/分,BP 17/11kPa,发育正常,营养中等,半卧位。皮肤黝黑,躯干四肢满布红、褐色豆大、甲大丘疹斑丘疹,表复鳞屑。全身浅表淋 POEMS syndrome is a multi-system disease, often accompanied by plasmacytoma. Clinical manifestations of complex misdiagnosis. This article reports 1 case. Male patient, 54 years old. Due to fever, cough, slightly dark red sputum, a daily dose of about 100 milliliters a month, on February 28, 1993 admission. No improvement with penicillin treatment. Chest tightness appeared a week ago, shortness of breath, can not lie down. Outside the hospital chest wear bloody pleural effusion. And lower extremity edema, intermittent row of gross hematuria. Examination: T 38 ℃, P 104 times / min, R 25 beats / min, BP 17 / 11kPa, normal development, moderate nutrition, semi-recumbent position. Dark skin, torso limbs covered with red, brown beans large, papules rash, table complex scales. Body superficial shower