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当前,麻痹性贝类中毒[Paralytic Shellfish Poisoning(PSP)]问题已为全世界所关注。在某些国家的特定海域一贯可食的贝类可突然被毒化,食用后即可引起食物中毒,严重者可致死亡。直到1937年Sommer等才提出这类中毒的原因是由于它们栖息的海水中存在某种有毒的甲藻类腰鞭毛藻(Dinoflagelltes)浮游生物所致。1957年Schantz等首先从毒化的加州贻贝(Mytilus californianus)和巨石房蛤(Saxidomus giganteus)中分别提取得到了纯毒素,定名为石房蛤毒素Saxitoxin(STX);并从甲藻类中的链状膝沟藻(G.catenella)的培养物中同样提取得到了STX,从而证明有
Currently, Paralytic Shellfish Poisoning (PSP) problem has been the world’s concern. Shellfish, which are consistently edible in selected areas of some countries, can suddenly be poisoned and can cause food poisoning when consumed and death in severe cases. It was not until 1937 that Sommer et al. Suggested that this poisoning was caused by the presence of dinoflagellates, a toxic dinoflagellate plankton, in the seawater inhabiting them. In 1957, Schantz et al. First obtained pure toxins from poisoned Mytilus californianus and Saxidomus giganteus respectively, and named them saxitoxin (STX). From the chains of dinoflagellates STX was similarly extracted from the culture of G. catenella to prove that there was