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目的探析妊娠期急性肾损伤患者的发病原因、临床特点、治疗方法和预后转归。方法对11例妊娠期急性肾损伤患者的临床资料进行回顾分析。结果 11例妊娠期急性肾损伤患者都根据病因和病情发展情况,采用相应的治疗方法 ,其中有6例终止了妊娠,3例自行阴道分娩,2例引产;7例早产儿,4例足月生产;有7例出现了新生儿窒息,发生率为63.7%;新生儿死亡5例,死亡率为45.5%。结论由妊娠期各种疾病所引起的妊娠血容量不足、肾血管痉挛、微血管性溶血以及毒物的损伤等因素是引起妊娠期急性肾功能衰竭的主要因素,其中重度妊高症引起的先兆子痫、子痫、胎盘早剥和感染性流产或引产引起的败血症、大出血、弥散性血管内凝血(DIC)是妊娠期急性肾损伤的主要因素,应该尽早发现发病原因并及时治疗,进而减少并发症和病死率。
Objective To investigate the causes, clinical features, treatment and outcome of patients with acute renal injury during pregnancy. Methods The clinical data of 11 patients with acute renal injury during pregnancy were retrospectively analyzed. Results All the 11 patients with acute renal injury during pregnancy were treated according to the etiology and condition. Among them, 6 patients terminated pregnancy, 3 had vaginal delivery, 2 had induced labor, 7 had premature infants and 4 had full-term Production; 7 cases of neonatal asphyxia, the incidence was 63.7%; neonatal death in 5 cases, the mortality rate was 45.5%. Conclusions Factors such as insufficient blood volume of pregnancy, renal vasospasm, microvascular hemolysis and toxic injury caused by various diseases during pregnancy are the main factors that cause acute renal failure during pregnancy. Among them, preeclampsia caused by severe pregnancy-induced hypertension , Eclampsia, placental abruption and sepsis caused by infectious abortion or induced labor, major bleeding, disseminated intravascular coagulation (DIC) is the main factor of acute renal injury in pregnancy, it should be found as soon as possible the cause of the disease and timely treatment, thereby reducing complications And mortality.