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绿色链球菌为感染性心内膜炎的最常见病因,本病的30％系由其引起,因此菌属正常口腔菌丛,故在心瓣膜感染前常先有牙、口腔、颌的感染史,基于其相对低毒性,故大多系侵入先前已损伤的心瓣膜,并导致典型的亚急性溃疡息肉型心内膜炎。组织学上见有心瓣膜受累处坏死,肉芽组织及血栓性疣赘物形成。炎性细胞通常以粒细胞为主。以组织细胞性或肉芽肿性反应为主者迄今仅见于Behcet的一例报道,而在感染性心内膜炎则至今尚未见报告。本文报道二例抗菌素类药物治疗不敏感的感染性心内膜炎伴组织细胞及部分肉芽肿反应的病例。
Streptococcus sobrinus is the most common cause of infective endocarditis, 30% of the disease caused by it, so the genus is a normal oral flora, it is often in the heart valve infection before the teeth, mouth, jaw infection history, Due to their relatively low toxicity, most often invade previously damaged heart valves and result in typical subacute ulcer polyposis endocarditis. Histologically, heart valve involvement necrosis, granulation tissue and thrombotic warts were formed. Inflammatory cells are usually granulocytes. So far the main cell or granulomatous reaction was found in only one case of Behcet, while in infective endocarditis has so far not been reported. This article reports two cases of antibiotic-insensitive infective endocarditis with tissue cells and partial granulomatous reaction cases.