抗β-受体自身抗体可能为β-受体功能紊乱的一个原因。它在鼻变态反应性疾病中的地位目前尚无研究。通过受体结合分析检测了常年性和季节性鼻变态反应性疾病患者的血清能否抑制β-受体功能,从而评价该自身抗体在鼻变态反应疾病中的病因学意义。 受试者包括螨致常年性鼻变态反应性疾病患者44例,日本杉花粉病患者41例,正常人41例。β-受体功 Anti-beta-adrenergic autoantibodies may be a cause of beta -receptor dysfunction. Its status in nasal allergy has not been studied yet. Receptor binding assays were used to determine whether sera from patients with perennial and seasonal nasal allergies can inhibit the beta -receptor function to evaluate the etiologic significance of this autoantibodies in nasal allergic diseases. The subjects included 44 cases of perennial allergic rhinitis, 41 cases of Japanese cedar pollenosis and 41 cases of normal subjects. β-receptor work