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目前,服口服避孕药仍是我国一部分妇女所采取的避孕措施。为了提高避孕效果,现将口服避孕药与其它类药物同时服用时的一些需注意的问题叙述如下: 1、口服避孕药加抗生素 与氨苄青霉素、羟氨苄青霉素、新霉素、四环素、氯霉素、红霉素等合用时,可抑制肠道正常菌群,而这些微生物又是葡萄糖醛酸酶的主要来源,口服避孕药需要这种酶的帮助,水解后才能吸收。因此,长期应用抗生素可使酶减少,而不利于口服避孕药的吸收,影响避孕效果。口服氨苄青霉素、
At present, oral contraceptives are still the contraceptive measures adopted by some women in our country. In order to improve the effect of contraception, the oral contraceptives and other drugs are taking some of the time to note the following issues: 1, oral contraceptives plus antibiotics and ampicillin, amoxicillin, neomycin, tetracycline, chloramphenicol , Erythromycin and other combinations, can inhibit the normal intestinal flora, and these microorganisms are the main source of glucuronidase, oral contraceptives need the help of this enzyme, after hydrolysis can be absorbed. Therefore, long-term use of antibiotics can reduce the enzyme, which is not conducive to the absorption of oral contraceptives, affecting the contraceptive effect. Oral ampicillin,