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目的:重点研究柴黄汤与西药治疗重症急性胰腺炎的临床疗效,以提供数据供内科保守治疗参考。方法:对2011年10月~2013年12月我院入院治疗的96例重症胰腺炎患者进行了详细的研究,将这些患者随机分为两组,对照组的患者给予常规的西药治疗,比如胃肠检验、禁食、补充体液、纠正电解质及酸碱失衡、抗感染治疗等等,观察组患者在上述常规西药治疗基础上,同时给予自拟柴黄汤,两组治疗方案都以14天为1个疗程。结果:经过研究,观察组患者肝脏相关指标的改善情况明显好于对照组,转氨酶的水平明显降低,两组比较差异有统计学意义(P<0.05);观察组患者的腹胀或腹痛、肠鸣音等临床症状的改善时间明显短于对照组,患者体温、淀粉酶恢复至正常时间以及住院的时间明显少于对照组,差异有统计学意义(P<0.05);经过2周的治疗,观察组组患者治疗后的APACHE II评分明显低于对照组患者对应的评分,差异有统计学意义(P<0.05);观察组患者的临床总有效率可达93.8%,这个数据明显高于对照组68.8%的总有效率,两组比较差异明显,有统计学意义(P<0.05)。结论:柴黄汤联合西药治疗重症急性胰腺炎的临床效果非常明显,能够更明显的改善患者临床症状及肝脏指标,临床应答率更高,值得在临床治疗中推广应用。
Objective: To study the clinical efficacy of Chaihuang Decoction and western medicine in the treatment of severe acute pancreatitis in order to provide data for reference of conservative treatment. Methods: A total of 96 patients with severe acute pancreatitis treated in our hospital from October 2011 to December 2013 were studied in detail. These patients were randomly divided into two groups. Patients in the control group were given conventional western medicine, such as stomach Intestinal test, fasting, body fluid replacement, correct electrolyte and acid-base imbalance, anti-infective therapy and so on. The observation group patients were treated with the above routine western medicine, A course of treatment. Results: After the study, the improvement of liver related indicators in the observation group was significantly better than that in the control group, and the level of aminotransferase was significantly lower in the observation group (P <0.05). The bloating or abdominal pain in the observation group, (P <0.05). After 2 weeks of treatment, the improvement of clinical symptoms was significantly shorter than that of the control group. The patients’ body temperature, amylase recovery to normal time and hospitalization time were significantly less than those in the control group The APACHE II score of the patients in the treatment group was significantly lower than that of the control group (P <0.05), and the total effective rate in the observation group was 93.8%, which was significantly higher than that of the control group 68.8% of the total effective rate, the difference was significant between the two groups, with statistical significance (P <0.05). Conclusion: The clinical effect of Chaihuang Decoction combined with Western medicine in the treatment of severe acute pancreatitis is very obvious. It can significantly improve the clinical symptoms and liver indexes of patients and has a higher clinical response rate. It is worth to be popularized and applied in clinical treatment.