Two novel lactams (2 and 8) with lowering effect on the elevated SGPT levels were isolatedfrom leaves of Clausenamide lansium (Lout.) Skeels. Structural elucidations on the basis of their spectrometric data combined with chemical reactions, their interrelationship and relation to clausenamidewere described. Two novel lactams (2 and 8) with lowering effect on the elevated SGPT levels were isolatedfrom leaves of Clausenamide lansium (Lout.) Skeels. Structural elucidations on the basis of their spectrometric data combined with chemical reactions, their interrelationship and relation to clausenamidewe described.