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目的:探讨血脂异常儿童与家族史的关系。方法:采用SynchronC×5 全自动化分析仪( 美国) 测定血清脂类五项指标,血脂异常儿童均进行一、二级直系亲属的家族史调查。结果:157 例高血脂儿童,有阳性家族史占38-2% ,而一、二级家族史中以患高血压者占首位,达43-9 % ,其次是冠心病占22-3 % 。有阳性家庭史儿童中血脂异常以LDLC值升高为主(x2 =4.98 P<0-05)而无家族史儿童血脂异常以HDLC 值下降为主(x2 = 13 .09 P< 0-01)。结论:高血压是促动脉硬化主因,家族史也起很大作用。
Objective: To explore the relationship between dyslipidemia children and family history. Methods: Five indicators of serum lipids were measured by SynchronC × 5 automatic analyzer (USA). The children with dyslipidemia were investigated by family history of primary and secondary immediate family members. Results: 157 cases of hypercholesterolemia, a positive family history accounted for 38-2%, while the first and second family history of hypertension in the first place, up to 43-9%, followed by coronary heart disease accounted for 22-3%. Children with positive family history of dyslipidemia with LDL C value-based (x2 = 4.98 P <0-05) and no family history of dyslipidemia with HDL C value decreased (x2 = 13 .09 P <0-01). Conclusion: Hypertension is the main cause of atherosclerosis and family history also plays a significant role.