对于环磷酰胺所致免疫功能低下模型小鼠 ,灌胃给予合成鱼腥草素 6 0mg/kg、12 0mg/kg能明显增加环磷酰胺所致免疫功能低下模型小鼠的脾脏指数、外周血淋巴细胞ANAE阳性百分率 ;增强单核巨噬细胞吞噬功能、迟发型超敏反应强度及ConA诱导的脾脏T淋巴细胞增殖能力 ;对胸腺指数则无明显影响 ;合成鱼腥草素 12 0mg/kg还能明显增强环磷酰胺模型小鼠血清溶血素的生成及脾脏空斑形成细胞溶血能力 . For immunosuppressive mice induced by cyclophosphamide, gavage of synthetic houttuyfonate 60 mg / kg and 120 mg / kg could significantly increase the spleen index of peripheral blood of immunosuppressed mice induced by cyclophosphamide, Lymphocyte ANAE-positive percentage; enhanced monocyte-macrophage phagocytosis, delayed-type hypersensitivity and ConA-induced spleen T lymphocyte proliferation; no significant effect on the thymus index; synthesis of Houttuyfonate 120mg / kg also Can significantly enhance the cyclophosphamide model mouse serum hemolysin production and hemolytic ability of spleen plaque-forming cells.